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BPS BPS-Pharmacotherapy Exam Syllabus Topics:

BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. From ethical and scientific validity standpoints, in addition to double blinding, which of the following research designs is best for determining a new medication's relative efficacy in treating acute stroke?

A) Placebo-controlled, randomized, parallel design
B) Crossover design comparing the new therapy with the best standard therapy
C) Placebo-controlled, crossover design
D) Parallel design comparing the new therapy with the best standard therapy

2. A 47-year-old patient with end-stage renal disease undergoing hemodialysis has an HCT of 23% and exhibits anginal symptoms. Upon further Workup, no evidence of occult bleeding is found.
In addition to antianginal therapy, which of the following is the most appropriate initial treatment for this patient's anemia?

A) Subcutaneous erythropoietin
B) Oral iron
C) Two units of PRBCs
D) Iron dextran

3. A 28 year old patient presents to a physician and reports persistent nasal discharge and facial tenderness for the past 15 days. The patient has no known drug allergies. Which recommendation would be best for treating this acute sinusitis?

A) Azithromycin
B) Sulfamethoxazole/trimethoprim
C) Amoxicillin/clavulanate acid
D) No antimicrobial indicated at this time

4. A 60-year-old man with heart failure states that he becomes "a bit short of breath" after climbing a flight of stairs. His ejection fraction is 40%. Current medications include lisinopril 5 mg daily, metoprolol XL 100 mg daily, aspirin 81 mg daily, furosemide 40 mg daily, and digoxin
250 mcg daily. All vital signs and laboratory values are stable and within normal limits. Which of the following recommendations would be most appropriate at this time?

A) Add Valsartan 80 mg twice daily.
B) Add spironolactone 25 mg daily.
C) Replace aspirin with clopidogrel 75 mg daily.
D) Increase lisinopril to 10 mg daily.

5. After the first intravenous bolus dose of a drug, the peak concentration is 50 mcg/mL, the elimination rate constant is 0.3/h, and the dosage Interval is 6 hours. Assuming a one compartment model and intravenous bolus injection, which of the following will be the peak concentration following the second dose?

A) 75 mcg/mL
B) 50mcg/mL
C) 58 mcg/mL
D) 64 mcg/mL

Solutions: